Spectrum of periodontal pockets microflora in patients with generalized periodontitis after use of the therapeutic composition based on decametoxin
DOI:
https://doi.org/10.33295/1992-576X-2022-5-6-26Keywords:
decamethoxine, propolis, ethonium, generalized periodontitis, microfloraAbstract
Goal. Improving the scheme of treatment and prevention of periodontal diseases using a therapeutic composition based on decamethoxine.
Materials and methods. 70 patients with diagnosed chronic generalized periodontitis (35 people – main group (A); 35 people – comparison group (B)) aged 25 to 45 years were treated. Clinical examination of patients was performed according to the generally accepted methods: subjective (complaints, medical history, life history) and objective (examination, index assessment, determination of the level of gingival attachment). We conducted a study of the quantitative composition and spectrum of the microflora of periodontal pockets in patients with generalized periodontitis on the indicators: CFU (colony forming units); study of morphological, tinktorial, cultural and biochemical properties of the isolated microflora with subsequent determination of its genus and species, study of the dynamics of changes in oral microbiocenosis in patients during their treatment and rehabilitation of the proposed composition of drugs.
Results. We identified decrease in the level of normal microflora, an increase in the number of opportunistic pathogens in patients with generalized periodontitis, the formation of dominant species of microorganisms or fungi; the presence of stable associations of microflora, fungi, protozoa. After treatment, there was a significant decrease in the number of pathogenic and opportunistic microflora in periodontal pockets in patients with generalized periodontitis.
Conclusion. The proposed pharmacological composition DEPS is an effective antiseptic, after the use of which there was a decrease in the number of pathogenic and opportunistic microflora of periodontal pockets. It can be used in the maintenance phase to improve the generally accepted treatment and prevention of periodontal disease.
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